Analysis of steroid hormone receptors in endometriotic tissues reveals chaotic results

Analysis of steroid hormone receptors in endometriotic tissues reveals chaotic results By Nasuhi Engin Aydin

  A group of researchers from academic institutions located at Australia and New Zeland, led by Dr. Holdsworth-Carson, have published their recent findings on steroid receptors in peritoneal endometriosis lesions by immunohistochemistry, in the journal Reproduvtive Biomedicine Online.  Endometriosis is…

Key Points Lay Summary

IL-33 Polarize Peritoneal Macrophages for Endometriosis Growth

IL-33 Polarize Peritoneal Macrophages for Endometriosis Growth By Nadire Duru

M2 type macrophages are the most common type of macrophages found in endometriosis and they enhance the development of endometriosis lesions. The key factors that stimulate macrophages to polarize towards M2 and contribute to the increased endometriosis lesions remain to be…

Key Points Lay Summary

Combination Therapy Proves More Efficient in the Treatment of Endometriosis

Combination Therapy Proves More Efficient in the Treatment of Endometriosis By Kasthuri Nair

In their recent paper in British Journal of Pharmacology, entitled “Combination therapy with telmisartan and parecoxib induces regression of endometriotic lesions,” Nenicu et al. illustrate the increased effectiveness of telmisartan used along with a cyclooxygenase-2 (COX-2) inhibitor (a non-steroidal anti-inflammatory…

Key Points Lay Summary